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From269US$ /night
Check-in
07Nov2025Select date
Check-out
08Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

3A Calle Oriente No 28 A, Antigua, Guatemala, 03001

Hotel Museo Spa Casa Santo Domingo, a 5-star accommodation, features a variety of amenities including a heated swimming pool, on-site dining, and access to multiple museums. This Antigua hotel, rated 8.9/10 on Booking.com, offers a unique blend of art, history, and wellness.

Rooms & Amenities

The spacious rooms at Hotel Museo Casa Santo Domingo, featuring artistic decor and local artwork, include 26 that embody the SPA Living concept. Each room is equipped with smart TVs, free Wi-Fi, and minibars, ensuring a comfortable stay.

Dining Options

Dining at the gourmet El Refectorio offers refined international dishes, crafted by renowned Chef Mario Enrique Campollo. Guests can also enjoy typical Guatemalan afternoon snacks on weekends and cocktails at the bar Cabildo.

Leisure & Activities

The hotel features a luxurious spa, complete with Jacuzzis, wet and dry saunas, and wellness treatments designed to restore balance. Guests may also explore the on-site museums, including the Museo de la Farmacia and Museo de Arte Pre-Colombino.

Business Services

For business travelers, Hotel Museo Spa Casa Santo Domingo provides various meeting spaces and planning services. The hotel is equipped to host congresses, seminars, and small meetings for up to 250 participants.

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Choose your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
King Room Spa Bath
2 persons
47 m² 
1 King-size bed
Fireplace
Air conditioning
Deluxe Double Room
2 persons
47 m² 
2 Double beds
Fireplace
Air conditioning
Standard Double Room
2 persons
35 m² 
2 Double beds
Fireplace
Air conditioning
Executive King Room
2 persons
47 m² 
1 King-size bed
Fireplace
Air conditioning
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Price and Room Availability

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Getting around

Comprehensive guide to transport options for seamless travel

City Centre
Antigua 1.0 km
Airports
La Aurora (GUA) 36.2 km

What our guests says about facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences
What’s included

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Currency exchange
  • ATM/Cash machine
  • Hairdresser
  • Smoke detectors
  • Fire extinguishers
  • Key access

Sports & Fitness

  • Fitness centre

Services

  • Paid airport shuttle
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots
  • Children's buffet

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Outdoor swimming pool
  • Beach umbrellas
  • Sun loungers
  • Sun terrace
  • Garden area
  • Spa & wellness centre
  • Solarium
  • Sauna
  • Steam room
  • Jacuzzi
  • Pedicure
  • Manicure
  • Waxing
  • Body scrub
  • Facial
  • Treatment room
  • Body wraps
  • Back massage
  • Head massage
  • Full body massage
  • Foot massage
  • Open-air bath
  • Make up services

Room features

  • Air conditioning
  • Mini-bar
  • Sitting area
  • Terrace
  • Garden furniture
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock
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Location

3A Calle Oriente No 28 A, Antigua, Guatemala, 03001
Map view
3A Calle Oriente No 28 A, Antigua, Guatemala, 03001
Nearby
3a Calle Oriente 28
Casa Santo Domingo Museums
510 m
4a Calle Oriente # 14 15C
ChocoMuseo
460 m
5a Calle Poniente
Palace of the Captain Generals
320 m
2a Avenida Norte y 2a Calle Oriente esquina. Antigua Guatemala
Convento de las Capuchinas
460 m
6a Calle Oriente
Tanque La Union
280 m
4 Calle Oriente # 10 Edificio El Jaulon
Casa del Jade
140 m
Museum
Casa Popenoe
410 m
Avenida 1a
Paseo De Los Museos
20 m
Museum
Casa Santo Domingo
320 m
Square
Antigua Guatemala
580 m
Church
Iglesia El Carmen
420 m
Museum
Antigua Guatemala Colonial Art Museum
570 m
Store
La bodegona
390 m
cnr 3a Calle Oriente & 3a Av Norte
Mercado de Artesanias El Carmen
440 m
3ra Avenida Norte # 20A
Healing Hands Therapy Spa
450 m
Restaurants
7 Caldos
30 m
Calle Oriente 3a
Arrin Cuan Antigua
60 m
Callejon Concepcion Casa #2
Samsara's Garden
200 m
6 Street West # 33 Interior
Akai Sushi & Oriental
150 m
4a Calle Oriente No. 39
Romeo y Julieta Guatemala
180 m
4a Calle Oriente 39 100m from Morjan gas station
El Convento
490 m
2 Avenida Norte No. 11
Welten
310 m
4a Calle Oriente No. 21
Bistrot Cinq
390 m
4 a Calle Oriente # 7 Centro Histórico
La Casa del Ron
380 m
4 Calle Oriente # 22 Salida Hacia la Capital

Reviews and Ratings

Reviews from guests about their experience.
Guest reviews
5.0/10
based on 5 reviews
9.0
9.0/10 based on 1455 reviews
Joe
United States, February  2025
8.2/10

I had a wonderful stay at this hotel with its unique blend of colonial and modern architecture. The gardens and ruins on the property are stunning, creating a serene atmosphere. While I found the rooms a bit dark and on the smaller side, they were well-furnished and comfortable. The service was top-notch, but I did find the bar overpriced. Overall, the experience was memorable, but there were aspects that could use some improvement.

Rooms
7.0
The rooms were beautifully furnished, but slightly dark and small, which might not suit everyone's taste.
Service
9.0
The service was excellent, with diligent and friendly team members helping me throughout my stay.
Location
10.0
This hotel is situated in the heart of a charming colonial city, surrounded by historic artifacts and beautiful landscapes.
Dining
7.0
The dining experience was generally good, especially breakfast, but I found the bar prices a bit excessive.
Facilities
8.0
The hotel offers great facilities, including a beautiful spa area and stunning gardens for relaxation.
Jay
United States, January  2025
9.6/10

Staying at Casa Santo Domingo was an exceptional experience! The stunning blend of historical architecture with modern amenities made for a truly unique atmosphere. The staff consistently went above and beyond to cater to our needs, and I was particularly impressed by the clean and well-maintained surroundings. On the downside, while breakfast was enjoyable, I wished there were more variety in options. Overall, it felt luxurious with a lot to offer at a great price.

Rooms
10.0
The rooms were spacious and beautifully designed, featuring a large bedroom and a fantastic bathroom with a jacuzzi. I particularly loved the charming terrace and the wood-burning fireplace, making it feel cozy.
Service
10.0
The staff was always polite, professional, and accommodating, making a genuine effort to ensure our stay was perfect.
Location
10.0
The hotel is set in beautifully landscaped grounds, rich in greenery, and it felt like a walk through history. Plus, there are great opportunities to explore on property museums.
Dining
9.0
The dining experience was excellent, with plenty of variety, and the private dinner we had was unforgettable.
Facilities
9.0
The facilities were impressive, including a spa and museums that enhanced the overall experience. A wonderful touch!
John
United States, January  2025
9.6/10

My stay at the hotel was truly unforgettable, offering a beautiful blend of luxury and historical charm. The breakfast was outstanding, and the attention to detail in the hotel's decor made for a captivating experience. However, the artistic pieces scattered throughout did come off as a bit intimidating for my taste. Overall, I found that this hotel offers great value for money, especially considering the unique ambiance and quality of services.

Rooms
9.0
The rooms were spacious, elegantly furnished, and very comfortable, providing a haven of relaxation after a day of exploration.
Service
10.0
The service was exceptional, with attentive and friendly staff always ready to assist, enhancing my experience throughout my stay.
Location
10.0
Located in the heart of Antigua, the hotel is a perfect base for exploring the charming streets filled with history and culture.
Dining
10.0
Dining was a highlight, with an array of local dishes that were both delicious and beautifully presented, making every meal a pleasure.
Facilities
9.0
The amenities, including a lovely pool area and on-site museum-like installations, provided ample options for relaxation and intrigue.
Rebecca
United States, November  2024
9.6/10

Staying at Casa Santo Domingo was a magical experience that exceeded my expectations in so many ways. The rich history and stunning architecture made the environment captivating, and the service was truly exceptional. However, its location a bit further from the town center might not be ideal for those wanting easy access to the bustling heart of Antigua, and the limited entertainment for children could be a concern for families. Overall, it was an excellent value for the luxurious experience I received.

Rooms
10.0
The rooms were fantastic, offering various styles and extremely spacious accommodations. I loved the attention to detail and the comfort they provided.
Service
10.0
The service was warm and accommodating. I felt genuinely cared for by the staff, especially after the minor incident we experienced.
Location
8.0
While the hotel is a bit removed from the main attractions, the beauty of the grounds and the nearby museum greatly compensate for it.
Dining
10.0
The dining experience was delightful, with a menu that truly celebrated local cuisine. Each meal was delicious, and the restaurant service was exceptional.
Facilities
10.0
The facilities, including the stunning spa and gardens, were well-maintained and added a layer of luxury to my stay. The free shuttle to the art garden offered a lovely adventure.
Frederick
United States, November  2024
9.8/10

Hotel Casa Santo Domingo is a delightful escape filled with stunning greenery and serene water features, providing a peaceful atmosphere. The staff is exceptionally accommodating, and my room was both cozy and immaculate, making for a comfortable stay. I highly recommend their weekend buffet for an incredible dining experience. The spa services were absolutely phenomenal; I left feeling rejuvenated. However, if you're looking for something outside the hotel, you might need to venture away to discover it, as much of the beauty is contained within the property.

Rooms
10.0
The rooms were incredibly cozy and comfortable, complete with traditional designs and modern amenities that made my stay enjoyable.
Service
10.0
The service was exceptionally attentive and pleasant, with staff always willing to meet my requests.
Location
9.0
The location is a beautiful oasis that feels removed from the outside world, yet it's close enough for walks to explore the vibrant local culture.
Dining
10.0
The dining experience was fantastic, especially during the Sunday buffet, where I was treated to fresh Guatemalan dishes and a variety of options.
Facilities
10.0
The facilities are beyond impressive, especially the spa, which provided an unparalleled relaxation experience.
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Check-in
07Nov2025Select date
Check-out
08Nov2025Select date
Rooms and Guests2 Guests, 1 Room